Silencing Heat Shock Protein 47 (HSP47) in Fibrogenic Precision-Cut Lung Slices: A Surprising Lack of Effects on Fibrogenesis?

Idiopathic pulmonary fibrosis (IPF) is a chronic disease that is characterized by the excessive deposition of scar tissue in the lungs. As currently available treatments are unable to restore lung function in patients, there is an urgent medical need for more effective drugs. Developing such drugs,...

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Vydáno v:Front Med (Lausanne)
Hlavní autoři: Ruigrok, Mitchel J. R., El Amasi, Khaled E. M., Leeming, Diana J., Sand, Jannie M. B., Frijlink, Henderik W., Hinrichs, Wouter L. J., Olinga, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917123/
https://ncbi.nlm.nih.gov/pubmed/33659262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2021.607962
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