Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron

Drug-induced kidney injury (DIKI) is a major concern in both drug development and clinical practice. There is an unmet need for biomarkers of glomerular damage and more distal renal injury in the loop of Henle and the collecting duct (CD). A cross-laboratory program to identify and characterize urin...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Chorley, Brian N, Ellinger-Ziegelbauer, Heidrun, Tackett, Michael, Simutis, Frank J, Harrill, Alison H, McDuffie, James, Atabakhsh, Elnaz, Nassirpour, Rounak, Whiteley, Laurence O, Léonard, Jean-François, Carswell, Gleta K, Harpur, Ernie, Chen, Connie L, Gautier, Jean-Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916737/
https://ncbi.nlm.nih.gov/pubmed/33367795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa181
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