Anti-Tumor Efficiency of Perillylalcohol/β-Cyclodextrin Inclusion Complexes in a Sarcoma S180-Induced Mice Model

The low solubility and high volatility of perillyl alcohol (POH) compromise its bioavailability and potential use as chemotherapeutic drug. In this work, we have evaluated the anticancer activity of POH complexed with β-cyclodextrin (β-CD) using three complexation approaches. Molecular docking sugge...

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Publicado en:Pharmaceutics
Main Authors: Rezende, Allan A., Santos, Rafael S., Andrade, Luciana N., Amaral, Ricardo G., Pereira, Matheus M., Bani, Cristiane, Chen, Mo, Priefer, Ronny, da Silva, Classius F., de Albuquerque Júnior, Ricardo L. C., Souto, Eliana B., Severino, Patrícia
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916601/
https://ncbi.nlm.nih.gov/pubmed/33578857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020245
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