Synthesis, Antitumor and Antibacterial Studies of New Shortened Analogues of (KLAKLAK)(2)-NH(2) and Their Conjugates Containing Unnatural Amino Acids

(1) Background: (KLAKLAK)(2) is a representative of the antimicrobial peptide group which also shows good anticancer properties. (2) Methods: Herein, we report synthesis using SPPS and characterization by HPLC/MS of a series of shortened analogues of (KLAKLAK)(2). They contain single sequence KLAKLA...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Jaber, Sirine, Iliev, Ivan, Angelova, Tsvetelina, Nemska, Veronica, Sulikovska, Inna, Naydenova, Emilia, Georgieva, Nelly, Givechev, Ivan, Grabchev, Ivo, Danalev, Dancho
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915940/
https://ncbi.nlm.nih.gov/pubmed/33567789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040898
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