The GAUGAA Motif Is Responsible for the Binding between circSMARCA5 and SRSF1 and Related Downstream Effects on Glioblastoma Multiforme Cell Migration and Angiogenic Potential

Circular RNAs (circRNAs) are a large class of RNAs with regulatory functions within cells. We recently showed that circSMARCA5 is a tumor suppressor in glioblastoma multiforme (GBM) and acts as a decoy for Serine and Arginine Rich Splicing Factor 1 (SRSF1) through six predicted binding sites (BSs)....

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Udgivet i:Int J Mol Sci
Main Authors: Barbagallo, Davide, Caponnetto, Angela, Barbagallo, Cristina, Battaglia, Rosalia, Mirabella, Federica, Brex, Duilia, Stella, Michele, Broggi, Giuseppe, Altieri, Roberto, Certo, Francesco, Caltabiano, Rosario, Barbagallo, Giuseppe Maria Vincenzo, Anfuso, Carmelina Daniela, Lupo, Gabriella, Ragusa, Marco, Di Pietro, Cinzia, Hansen, Thomas Birkballe, Purrello, Michele
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915938/
https://ncbi.nlm.nih.gov/pubmed/33562358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041678
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