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Targeting and Reprograming Cancer-Associated Fibroblasts and the Tumor Microenvironment in Pancreatic Cancer

SIMPLE SUMMARY: The tumor microenvironment plays a major role in the progression and drug resistance of pancreatic cancer. Cancer-associated fibroblasts are the major stromal cells and source of extracellular matrix proteins forming the dense stromal tumor microenvironment. Targeting cancer-associat...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sunami, Yoshiaki, Böker, Viktoria, Kleeff, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915918/
https://ncbi.nlm.nih.gov/pubmed/33572223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040697
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