Complementary Effects of Carbamylated and Citrullinated LL37 in Autoimmunity and Inflammation in Systemic Lupus Erythematosus

LL37 acts as T-cell/B-cell autoantigen in Systemic lupus erythematosus (SLE) and psoriatic disease. Moreover, when bound to “self” nucleic acids, LL37 acts as “danger signal,” leading to type I interferon (IFN-I)/pro-inflammatory factors production. T-cell epitopes derived from citrullinated-LL37 ac...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lande, Roberto, Pietraforte, Immacolata, Mennella, Anna, Palazzo, Raffaella, Spinelli, Francesca Romana, Giannakakis, Konstantinos, Spadaro, Francesca, Falchi, Mario, Riccieri, Valeria, Stefanantoni, Katia, Conrad, Curdin, Alessandri, Cristiano, Conti, Fabrizio, Frasca, Loredana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915858/
https://ncbi.nlm.nih.gov/pubmed/33562078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041650
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