Urinary Titin N-Fragment as a Biomarker of Muscle Atrophy, Intensive Care Unit-Acquired Weakness, and Possible Application for Post-Intensive Care Syndrome

Titin is a giant protein that functions as a molecular spring in sarcomeres. Titin interconnects the contraction of actin-containing thin filaments and myosin-containing thick filaments. Titin breaks down to form urinary titin N-fragments, which are measurable in urine. Urinary titin N-fragment was...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Med
Hauptverfasser: Nakanishi, Nobuto, Tsutsumi, Rie, Hara, Kanako, Matsuo, Masafumi, Sakaue, Hiroshi, Oto, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915692/
https://ncbi.nlm.nih.gov/pubmed/33561946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10040614
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