Selective Targeting of Cancer-Associated Fibroblasts by Engineered H-Ferritin Nanocages Loaded with Navitoclax

Cancer-associated fibroblasts (CAFs) are key actors in regulating cancer progression. They promote tumor growth, metastasis formation, and induce drug resistance. For these reasons, they are emerging as potential therapeutic targets. Here, with the aim of developing CAF-targeted drug delivery agents...

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Pubblicato in:Cells
Autori principali: Sitia, Leopoldo, Bonizzi, Arianna, Mazzucchelli, Serena, Negri, Sara, Sottani, Cristina, Grignani, Elena, Rizzuto, Maria Antonietta, Prosperi, Davide, Sorrentino, Luca, Morasso, Carlo, Allevi, Raffaele, Sevieri, Marta, Silva, Filippo, Truffi, Marta, Corsi, Fabio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915356/
https://ncbi.nlm.nih.gov/pubmed/33562504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020328
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