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Biochemical and Computational Studies of the Interaction between a Glucosamine Derivative, NAPA, and the IKKα Kinase
The glucosamine derivative 2-(N-Acetyl)-L-phenylalanylamido-2-deoxy- [Formula: see text]-D-glucose (NAPA), was shown to inhibit the kinase activity of IKK [Formula: see text] , one of the two catalytic subunits of IKK complex, decreasing the inflammatory status in osteoarthritis chondrocytes. In the...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7915277/ https://ncbi.nlm.nih.gov/pubmed/33562013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041643 |
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