Biochemical and Computational Studies of the Interaction between a Glucosamine Derivative, NAPA, and the IKKα Kinase

The glucosamine derivative 2-(N-Acetyl)-L-phenylalanylamido-2-deoxy- [Formula: see text]-D-glucose (NAPA), was shown to inhibit the kinase activity of IKK [Formula: see text] , one of the two catalytic subunits of IKK complex, decreasing the inflammatory status in osteoarthritis chondrocytes. In the...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Lopreiato, Mariangela, Di Cristofano, Samuele, Cocchiola, Rossana, Mariano, Alessia, Guerrizio, Libera, Scandurra, Roberto, Mosca, Luciana, Raimondo, Domenico, d’Abusco, Anna Scotto
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915277/
https://ncbi.nlm.nih.gov/pubmed/33562013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041643
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