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Development and Validation of an Automated Zone Fluidics-Based Sensor for In Vitro Dissolution Studies of Captopril Using Total Error Concept

In the present research, a zone fluidics-based automated sensor for the analysis of captopril in in vitro dissolution samples is reported. Captopril is reacted under flow conditions with Ni(II) (10 mmol L(−1)) in alkaline medium (0.15% v/v NH(3)) to form a stable derivate, which is monitored spectro...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Karakosta, Theano D., Tzanavaras, Paraskevas D., Zacharis, Constantinos K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914990/
https://ncbi.nlm.nih.gov/pubmed/33562585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040824
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