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Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications

The widely used rat uterotrophic assay to assess known and potential estrogenic compounds only considers uterine weight gain as endpoint measurement. To complement this method with an advanced technology that reveals molecular targets, we analyzed changes in protein expression using label-free quant...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Prokai, Laszlo, Rahlouni, Fatima, Zaman, Khadiza, Nguyen, Vien, Prokai-Tatrai, Katalin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914934/
https://ncbi.nlm.nih.gov/pubmed/33567512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041686
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