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Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications

The widely used rat uterotrophic assay to assess known and potential estrogenic compounds only considers uterine weight gain as endpoint measurement. To complement this method with an advanced technology that reveals molecular targets, we analyzed changes in protein expression using label-free quant...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Prokai, Laszlo, Rahlouni, Fatima, Zaman, Khadiza, Nguyen, Vien, Prokai-Tatrai, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914934/
https://ncbi.nlm.nih.gov/pubmed/33567512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041686
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