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A Human Cellular Model for Colorectal Anastomotic Repair: The Effect of Localization and Transforming Growth Factor-β1 Treatment on Collagen Deposition and Biomarkers

Anastomotic leakage (AL) is a devastating complication after colorectal surgery, possibly due to the loss of stabilizing collagen fibers in the submucosa. Our aim was to assess the formation of collagen in the colon versus the rectum with or without transforming growth factor (TGF)-β1 exposure in a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Türlü, Ceylan, Willumsen, Nicholas, Marando, Debora, Schjerling, Peter, Biskup, Edyta, Hannibal, Jens, Jorgensen, Lars N., Ågren, Magnus S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914853/
https://ncbi.nlm.nih.gov/pubmed/33562728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041616
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