A Multifocal Pediatric Papillary Thyroid Carcinoma (PTC) Harboring the AGK-BRAF and RET/PTC3 Fusion in a Mutually Exclusive Pattern Reveals Distinct Levels of Genomic Instability and Nuclear Organization

SIMPLE SUMMARY: Genetic alterations, such as RET/PTC and AGK-BRAF fusions, are frequent events in pediatric papillary thyroid carcinoma (PTC). However, their role as prognostic markers in pediatric PTC is still under investigation. In this study, we present a patient harboring three tumor foci with...

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Bibliographische Detailangaben
Veröffentlicht in:Biology (Basel)
Hauptverfasser: Sisdelli, Luiza, Cordioli, Maria Isabel V., Vaisman, Fernanda, Monte, Osmar, Longui, Carlos A., Cury, Adriano N., Freitas, Monique O., Rangel-Pozzo, Aline, Mai, Sabine, Cerutti, Janete M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Case Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914679/
https://ncbi.nlm.nih.gov/pubmed/33562578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10020125
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