Sunitinib-induced cardiac hypertrophy and the endothelin axis

Anti-angiogenics drugs in clinical use for cancer treatment induce cardiotoxic side effects. The endothelin axis is involved in hypertension and cardiac remodelling, and addition of an endothelin receptor antagonist to the anti-angiogenic sunitinib was shown to reduce cardiotoxicity of sunitinib in...

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Bibliografische gegevens
Gepubliceerd in:Theranostics
Hoofdauteurs: Sourdon, Joevin, Facchin, Caterina, Certain, Anaïs, Viel, Thomas, Robin, Blaise, Lager, Franck, Marchiol, Carmen, Balvay, Daniel, Yoganathan, Thulaciga, Favier, Judith, Tharaux, Pierre-Louis, Dhaun, Neeraj, Renault, Gilles, Tavitian, Bertrand
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2021
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914356/
https://ncbi.nlm.nih.gov/pubmed/33664864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.49837
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