Sunitinib-induced cardiac hypertrophy and the endothelin axis

Anti-angiogenics drugs in clinical use for cancer treatment induce cardiotoxic side effects. The endothelin axis is involved in hypertension and cardiac remodelling, and addition of an endothelin receptor antagonist to the anti-angiogenic sunitinib was shown to reduce cardiotoxicity of sunitinib in...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Sourdon, Joevin, Facchin, Caterina, Certain, Anaïs, Viel, Thomas, Robin, Blaise, Lager, Franck, Marchiol, Carmen, Balvay, Daniel, Yoganathan, Thulaciga, Favier, Judith, Tharaux, Pierre-Louis, Dhaun, Neeraj, Renault, Gilles, Tavitian, Bertrand
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914356/
https://ncbi.nlm.nih.gov/pubmed/33664864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.49837
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