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TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO
Sensing of pathogenic nucleic acids by pattern recognition receptors (PRR) not only initiates anti-microbe defense but causes inflammatory and autoimmune diseases. E3 ubiquitin ligase(s) critical in innate response need to be further identified. Here we report that the tripartite motif-containing E3...
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| Publicado no: | Signal Transduct Target Ther |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7914255/ https://ncbi.nlm.nih.gov/pubmed/33640899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00477-8 |
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