Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin α(v)β(5) Signaling Pathway

INTRODUCTION: As the primary immune cells, macrophages play a key role in atherosclerotic progression. M2 macrophage polarization has been reported to promote tissue repair and attenuate plaque formation upon the expression of anti-inflammatory factors. Convallatoxin (CNT) is a natural cardiac glyco...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Yi, Shi, Xiujin, Han, Jialun, Peng, Wenxing, Fang, Zhenwei, Zhou, Yang, Xu, Xiaoyu, Lin, Jie, Xiao, Fucheng, Zhao, Limin, Lin, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914072/
https://ncbi.nlm.nih.gov/pubmed/33654384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S288728
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