Isoquinolinequinone Derivatives from a Marine Sponge (Haliclona sp.) Regulate Inflammation in In Vitro System of Intestine

Using bio-guided fractionation and based on the inhibitory activities of nitric oxide (NO) and prostaglandin E2 (PGE2), eight isoquinolinequinone derivatives (1–8) were isolated from the marine sponge Haliclona sp. Among these, methyl O-demethylrenierate (1) is a noble ester, whereas compounds 2 and...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Kim, Yun Na, Ji, Yeong Kwang, Kim, Na-Hyun, Van Tu, Nguyen, Rho, Jung-Rae, Jeong, Eun Ju
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913985/
https://ncbi.nlm.nih.gov/pubmed/33557170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19020090
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