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Role of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation and Subsequent Immune Challenge in the Behaviour and Microglial Cell Trajectory in Adult Offspring: A Study of the Neurodevelopmental Model of Schizophrenia

Multiple lines of evidence support the pathogenic role of maternal immune activation (MIA) in the occurrence of the schizophrenia-like disturbances in offspring. While in the brain the homeostatic role of neuron-microglia protein systems is well documented, the participation of the CX3CL1-CX3CR1 and...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chamera, Katarzyna, Trojan, Ewa, Kotarska, Katarzyna, Szuster-Głuszczak, Magdalena, Bryniarska, Natalia, Tylek, Kinga, Basta-Kaim, Agnieszka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913889/
https://ncbi.nlm.nih.gov/pubmed/33557113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041558
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