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Dangerous Stops: Nonsense Mutations Can Dramatically Increase Frequency of Prion Conversion

Amyloid formation is associated with many incurable diseases. For some of these, sporadic cases are much more common than familial ones. Some reports point to the role of somatic cell mosaicism in these cases via origination of amyloids in a limited number of cells, which can then spread through tis...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Dergalev, Alexander A., Urakov, Valery N., Agaphonov, Michael O., Alexandrov, Alexander I., Kushnirov, Vitaly V.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913716/
https://ncbi.nlm.nih.gov/pubmed/33546497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041542
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