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Human pathways in animal models: possibilities and limitations

Animal models are crucial for advancing our knowledge about the molecular pathways involved in human diseases. However, it remains unclear to what extent tissue expression of pathways in healthy individuals is conserved between species. In addition, organism-specific information on pathways in anima...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Doncheva, Nadezhda T, Palasca, Oana, Yarani, Reza, Litman, Thomas, Anthon, Christian, Groenen, Martien A M, Stadler, Peter F, Pociot, Flemming, Jensen, Lars J, Gorodkin, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913694/
https://ncbi.nlm.nih.gov/pubmed/33524155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab012
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