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Non-perfectly matching small RNAs can induce stable and heritable epigenetic modifications and can be used as molecular markers to trace the origin and fate of silencing RNAs

Short non-coding RNA molecules (sRNAs) play a fundamental role in gene regulation and development in higher organisms. They act as molecular postcodes and guide AGO proteins to target nucleic acids. In plants, sRNA-targeted mRNAs are degraded, reducing gene expression. In contrast, sRNA-targeted DNA...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Fei, Yue, Nyikó, Tünde, Molnar, Attila
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913690/
https://ncbi.nlm.nih.gov/pubmed/33524108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab023
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