In vitro selected GUAA tetraloop-binding receptors with structural plasticity and evolvability towards natural RNA structural modules

GNRA tetraloop-binding receptor interactions are key components in the macromolecular assembly of a variety of functional RNAs. In nature, there is an apparent bias for GAAA/11nt receptor and GYRA/helix interactions, with the former interaction being thermodynamically more stable than the latter. Wh...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Zakrevsky, Paul, Calkins, Erin, Kao, Yi-Ling, Singh, Gurkeerat, Keleshian, Vasken L, Baudrey, Stephanie, Jaeger, Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Structural Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913685/
https://ncbi.nlm.nih.gov/pubmed/33524109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab021
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