Repression of a large number of genes requires interplay between homologous recombination and HIRA

During homologous recombination, Dbl2 protein is required for localisation of Fbh1, an F-box helicase that efficiently dismantles Rad51–DNA filaments. RNA-seq analysis of dbl2Δ transcriptome showed that the dbl2 deletion results in upregulation of more than 500 loci in Schizosaccharomyces pombe. Com...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Misova, Ivana, Pitelova, Alexandra, Budis, Jaroslav, Gazdarica, Juraj, Sedlackova, Tatiana, Jordakova, Anna, Benko, Zsigmond, Smondrkova, Maria, Mayerova, Nina, Pichlerova, Karoline, Strieskova, Lucia, Prevorovsky, Martin, Gregan, Juraj, Cipak, Lubos, Szemes, Tomas, Polakova, Silvia Bagelova
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913671/
https://ncbi.nlm.nih.gov/pubmed/33511417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab027
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