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Biased Brownian Motion of KIF1A and the Role of Tubulin’s C-Terminal Tail Studied by Molecular Dynamics Simulation

KIF1A is a kinesin family protein that moves over a long distance along the microtubule (MT) to transport synaptic vesicle precursors in neurons. A single KIF1A molecule can move toward the plus-end of MT in the monomeric form, exhibiting the characteristics of biased Brownian motion. However, how t...

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Pubblicato in:Int J Mol Sci
Autori principali: Mizuhara, Yukinobu, Takano, Mitsunori
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913626/
https://ncbi.nlm.nih.gov/pubmed/33557020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041547
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