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Combination Regimens of Favipiravir Plus Interferon Alpha Inhibit Chikungunya Virus Replication in Clinically Relevant Human Cell Lines

Chikungunya virus (CHIKV) is an alphavirus associated with a broad tissue tropism for which no antivirals or vaccines are approved. This study evaluated the antiviral potential of favipiravir (FAV), interferon-alpha (IFN), and ribavirin (RBV) against CHIKV as mono- and combination-therapy in cell li...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Franco, Evelyn J., Tao, Xun, Hanrahan, Kaley C., Zhou, Jieqiang, Bulitta, Jürgen B., Brown, Ashley N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912990/
https://ncbi.nlm.nih.gov/pubmed/33540830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9020307
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