Single Strain High-Depth NGS Reveals High rDNA (ITS-LSU) Variability in the Four Prevalent Pathogenic Species of the Genus Candida

Ribosomal RNA in fungi is encoded by a series of genes and spacers included in a large operon present in 100 tandem repeats, normally in a single locus. The multigene nature of this locus was somehow masked by Sanger sequencing, which produces a single sequence reporting the prevalent nucleotide of...

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Foilsithe in:Microorganisms
Main Authors: Colabella, Claudia, Casagrande Pierantoni, Debora, Corte, Laura, Roscini, Luca, Conti, Angela, Bassetti, Matteo, Tascini, Carlo, Robert, Vincent, Cardinali, Gianluigi
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912828/
https://ncbi.nlm.nih.gov/pubmed/33540602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9020302
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