Загрузка...

Design, Synthesis, Anticancer Activity, and Solid Lipid Nanoparticle Formulation of Indole- and Benzimidazole-Based Compounds as Pro-Apoptotic Agents Targeting Bcl-2 Protein

Cancer is a multifactorial disease necessitating identification of novel targets for its treatment. Inhibition of Bcl-2 for triggered pro-apoptotic signaling is considered a promising strategy for cancer treatment. Within the current work, we aimed to design and synthesize a new series of benzimidaz...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Pharmaceuticals (Basel)
Главные авторы: Nagy, Manar I., Darwish, Khaled M., Kishk, Safaa M., Tantawy, Mohamed A., Nasr, Ali M., Qushawy, Mona, Swidan, Shady A., Mostafa, Samia M., Salama, Ismail
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912796/
https://ncbi.nlm.nih.gov/pubmed/33535550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14020113
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!