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Liposomal Bupivacaine (Bupigel) Demonstrates Minimal Local Nerve Toxicity in a Rabbit Functional Model

We previously reported the development of a novel formulation of an ultra-long-acting local anesthetic based on bupivacaine encapsulated in large multivesicular liposomes (Bupisomes) embedded in hydrogel. This formulation (Bupigel) prolonged bupivacaine release from the formulation in dissolution-li...

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Publicat a:Pharmaceutics
Autors principals: Bavli, Yaelle, Rabie, Malcolm, Fellig, Yakov, Nevo, Yoram, Barenholz, Yechezkel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912710/
https://ncbi.nlm.nih.gov/pubmed/33535418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020185
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