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Assessing the Mechanism of Fluoxetine-Mediated CYP2D6 Inhibition
Fluoxetine is still one of the most widely used antidepressants in the world. The drug is extensively metabolized by several cytochrome P450 (CYP450) enzymes and subjected to a myriad of CYP450-mediated drug interactions. In a multidrug regimen, preemptive mitigation of drug–drug interactions requir...
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| Veröffentlicht in: | Pharmaceutics |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7912198/ https://ncbi.nlm.nih.gov/pubmed/33498694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020148 |
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