High Antiproliferative Activity of Hydroxythiopyridones over Hydroxypyridones and Their Organoruthenium Complexes

Hydroxypyr(id)ones are a pharmaceutically important class of compounds that have shown potential in diverse areas of drug discovery. We investigated the 3-hydroxy-4-pyridones 1a–1c and 3-hydroxy-4-thiopyridones 1d–1f as well as their Ru(η(6)-p-cymene)Cl complexes 2a–2f, and report here the molecular...

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Veröffentlicht in:Biomedicines
Hauptverfasser: Shakil, Md. Salman, Parveen, Shahida, Rana, Zohaib, Walsh, Fearghal, Movassaghi, Sanam, Söhnel, Tilo, Azam, Mayur, Shaheen, Muhammad Ashraf, Jamieson, Stephen M. F., Hanif, Muhammad, Rosengren, Rhonda J., Hartinger, Christian G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912191/
https://ncbi.nlm.nih.gov/pubmed/33513800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020123
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