Small Molecule-Based Enzyme Inhibitors in the Treatment of Primary Hyperoxalurias

Primary hyperoxalurias (PHs) are a group of inherited alterations of the hepatic glyoxylate metabolism. PHs classification based on gene mutations parallel a variety of enzymatic defects, and all involve the harmful accumulation of calcium oxalate crystals that produce systemic damage. These geograp...

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Detalhes bibliográficos
Publicado no:J Pers Med
Main Authors: Moya-Garzon, Maria Dolores, Gomez-Vidal, Jose Antonio, Alejo-Armijo, Alfonso, Altarejos, Joaquin, Rodriguez-Madoz, Juan Roberto, Fernandes, Miguel Xavier, Salido, Eduardo, Salido, Sofia, Diaz-Gavilan, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912158/
https://ncbi.nlm.nih.gov/pubmed/33513899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11020074
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