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From Transcriptomics to Treatment in Inherited Optic Neuropathies

Inherited optic neuropathies, including Leber Hereditary Optic Neuropathy (LHON) and Dominant Optic Atrophy (DOA), are monogenetic diseases with a final common pathway of mitochondrial dysfunction leading to retinal ganglion cell (RGC) death and ultimately loss of vision. They are, therefore, excell...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Gilhooley, Michael James, Owen, Nicholas, Moosajee, Mariya, Yu Wai Man, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912133/
https://ncbi.nlm.nih.gov/pubmed/33499292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12020147
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