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Mechanisms of Intranasal Deferoxamine in Neurodegenerative and Neurovascular Disease

Identifying disease-modifying therapies for neurological diseases remains one of the greatest gaps in modern medicine. Herein, we present the rationale for intranasal (IN) delivery of deferoxamine (DFO), a high-affinity iron chelator, as a treatment for neurodegenerative and neurovascular disease wi...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Kosyakovsky, Jacob, Fine, Jared M., Frey, William H., Hanson, Leah R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911954/
https://ncbi.nlm.nih.gov/pubmed/33513737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14020095
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