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Ablation of SMUG1 Reduces Cell Viability and Increases UVC-Mediated Apoptosis in Hepatocarcinoma HepG2 Cells

Uracil is an unavoidable aberrant base in DNA sequences, the repair of which takes place by a highly efficient base excision repair mechanism. The removal of uracil from the genome requires multiple biochemical steps with conformational changes of DNA that inhibit DNA replication and interfere with...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: An, Mi-Jin, Shin, Geun-Seup, Lee, Hyun-Min, Kim, Jung-Woong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911780/
https://ncbi.nlm.nih.gov/pubmed/33573186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12020201
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