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Development of a Hierarchical Support Vector Regression-Based In Silico Model for Caco-2 Permeability

Drug absorption is one of the critical factors that should be taken into account in the process of drug discovery and development. The human colon carcinoma cell layer (Caco-2) model has been frequently used as a surrogate to preliminarily investigate the intestinal absorption. In this study, a quan...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Ta, Giang Huong, Jhang, Cin-Syong, Weng, Ching-Feng, Leong, Max K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911528/
https://ncbi.nlm.nih.gov/pubmed/33525340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020174
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