Amoxicillin and Clarithromycin Mucoadhesive Delivery System for Helicobacter pylori Infection in a Mouse Model: Characterization, Pharmacokinetics, and Efficacy

Helicobacter pylori is the main pathogen responsible for gastric ulcers and a predisposing factor of stomach cancer. Although current treatment is usually successful, it requires high doses and frequent administration. An innovative mucoadhesive system (Mucolast(®)) loaded with amoxicillin and clari...

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Publicat a:Pharmaceutics
Autors principals: Villegas, Isabel, Rosillo, María Ángeles, Alarcón-de-la-Lastra, Catalina, Vázquez-Román, Victoria, Llorente, Maria, Sánchez, Susana, Gil, Ana Gloria, Alcalde, Pilar, González, Esther, Rosell, Elisabet, Nieto, Carles, Fernandez-Campos, Francisco
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911155/
https://ncbi.nlm.nih.gov/pubmed/33498958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020153
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