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Rescuing the Last-Line Polymyxins: Achievements and Challenges

Antibiotic resistance is a major global health challenge and, worryingly, several key Gram negative pathogens can become resistant to most currently available antibiotics. Polymyxins have been revived as a last-line therapeutic option for the treatment of infections caused by multidrug-resistant Gra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Rev
Hauptverfasser: Nang, Sue C., Azad, Mohammad A. K., Velkov, Tony, Zhou, Qi (Tony), Li, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911091/
https://ncbi.nlm.nih.gov/pubmed/33627412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pharmrev.120.000020
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