Orientation of Antigen Display on Self-Assembling Protein Nanoparticles Influences Immunogenicity

Self-assembling protein nanoparticles (SAPN) serve as a repetitive antigen delivery platform with high-density epitope display; however, antigen characteristics such as size and epitope presentation can influence the immunogenicity of the assembled particle and are aspects to consider for a rational...

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Publicat a:Vaccines (Basel)
Autors principals: Schneider, Cosette G., Taylor, Justin A., Sibilo, Michael Q., Miura, Kazutoyo, Mallory, Katherine L., Mann, Christopher, Karch, Christopher, Beck, Zoltan, Matyas, Gary R., Long, Carole A., Bergmann-Leitner, Elke, Burkhard, Peter, Angov, Evelina
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911071/
https://ncbi.nlm.nih.gov/pubmed/33572803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9020103
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