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Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy

BACKGROUND: The immunological mechanisms responsible for protection against malaria infection vary among Plasmodium species, host species and the developmental stage of parasite, and are poorly understood. A challenge with live parasites is the most relevant approach to testing the efficacy of exper...

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Detalhes bibliográficos
Main Authors: Leitner, Wolfgang W, Bergmann-Leitner, Elke S, Angov, Evelina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904356/
https://ncbi.nlm.nih.gov/pubmed/20507620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-145
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