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Interaction between Parkin and α-Synuclein in PARK2-Mediated Parkinson’s Disease
Parkin and α-synuclein are two key proteins involved in the pathophysiology of Parkinson’s disease (PD). Neurotoxic alterations of α-synuclein that lead to the formation of toxic oligomers and fibrils contribute to PD through synaptic dysfunction, mitochondrial impairment, defective endoplasmic reti...
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| Publié dans: | Cells |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7911026/ https://ncbi.nlm.nih.gov/pubmed/33572534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020283 |
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