Interaction between Parkin and α-Synuclein in PARK2-Mediated Parkinson’s Disease

Parkin and α-synuclein are two key proteins involved in the pathophysiology of Parkinson’s disease (PD). Neurotoxic alterations of α-synuclein that lead to the formation of toxic oligomers and fibrils contribute to PD through synaptic dysfunction, mitochondrial impairment, defective endoplasmic reti...

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Udgivet i:Cells
Main Authors: Madsen, Daniel Aghaie, Schmidt, Sissel Ida, Blaabjerg, Morten, Meyer, Morten
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911026/
https://ncbi.nlm.nih.gov/pubmed/33572534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020283
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