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Injectable Glycol Chitosan Hydrogel Containing Folic Acid-Functionalized Cyclodextrin-Paclitaxel Complex for Breast Cancer Therapy

We prepared a drug carrier which consisted of injectable methacrylated glycol chitosan (MGC) hydrogel, and a conjugate of 6-monodeoxy-6-monoamino-β-cyclodextrin⋅hydrochloride (6-NH(2)-β-CD⋅HCl), polyethylene glycol (PEG), and folic acid (FA) for the local delivery and improved cellular uptake of pac...

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Détails bibliographiques
Publié dans:Nanomaterials (Basel)
Auteurs principaux: Hyun, Hoon, Park, Min Ho, Jo, Gayoung, Lee, Bo Young, Choi, Jae Won, Chun, Heung Jae, Kim, Hyeon Soo, Yang, Dae Hyeok
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910883/
https://ncbi.nlm.nih.gov/pubmed/33513732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano11020317
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