Immune monitoring in mesothelioma patients identifies novel immune-modulatory functions of gemcitabine associating with clinical response

BACKGROUND: Gemcitabine is a frequently used chemotherapeutic agent but its effects on the immune system are incompletely understood. Recently, the randomized NVALT19-trial revealed that maintenance gemcitabine after first-line chemotherapy significantly prolonged progression-free survival (PFS) com...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Dammeijer, Floris, De Gooijer, Cornedine J., van Gulijk, Mandy, Lukkes, Melanie, Klaase, Larissa, Lievense, Lysanne A., Waasdorp, Cynthia, Jebbink, Merel, Bootsma, Gerben P., Stigt, Jos A., Biesma, Bonne, Kaijen-Lambers, Margaretha E.H., Mankor, Joanne, Vroman, Heleen, Cornelissen, Robin, Baas, Paul, Van der Noort, Vincent, Burgers, Jacobus A., Aerts, Joachim G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910686/
https://ncbi.nlm.nih.gov/pubmed/33516644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103160
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