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A correlation analysis to assess event-free survival as a trial-level surrogate for overall survival in early breast cancer

BACKGROUND: Event-free survival (EFS) has been listed on the FDA Table of Surrogate Endpoints as a surrogate measure that can be considered for accelerated or traditional approval in breast cancer. However, no studies have evaluated the correlation between the treatment effects on EFS and treatment...

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Detalhes bibliográficos
Publicado no:EClinicalMedicine
Main Authors: Gyawali, Bishal, D'Andrea, Elvira, Franklin, Jessica M., Kesselheim, Aaron S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910654/
https://ncbi.nlm.nih.gov/pubmed/33681740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2021.100730
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