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Characterization of Gene Therapy Associated Uveitis Following Intravitreal Adeno-Associated Virus Injection in Mice

PURPOSE: To characterize the intraocular immune cell infiltrate induced by intravitreal adeno-associated virus (AAV) gene therapy. METHODS: AAV vectors carrying plasmids expressing green fluorescent protein under the control of PR2.1 were injected intravitreally into AAV naive and AAV primed C57Bl/6...

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Библиографические подробности
Опубликовано в: :Invest Ophthalmol Vis Sci
Главные авторы: Tummala, Gayathri, Crain, Adam, Rowlan, Jessica, Pepple, Kathryn L.
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910624/
https://ncbi.nlm.nih.gov/pubmed/33630023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.2.41
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