The Campylobacter jejuni CiaD effector co-opts the host cell protein IQGAP1 to promote cell entry

Campylobacter jejuni is a foodborne pathogen that binds to and invades the epithelial cells lining the human intestinal tract. Maximal invasion of host cells by C. jejuni requires cell binding as well as delivery of the Cia proteins (Campylobacter invasion antigens) to the host cell cytosol via the...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Negretti, Nicholas M., Gourley, Christopher R., Talukdar, Prabhat K., Clair, Geremy, Klappenbach, Courtney M., Lauritsen, Cody J., Adkins, Joshua N., Konkel, Michael E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910587/
https://ncbi.nlm.nih.gov/pubmed/33637714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21579-5
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