PET/CT Imaging of (89)Zr-N-sucDf-Pembrolizumab in Healthy Cynomolgus Monkeys

PURPOSE: Programmed cell death-1 receptor (PD-1) and its ligand (PD-L1) are the targets for immunotherapy in many cancer types. Although PD-1 blockade has therapeutic effects, the efficacy differs between patients. Factors contributing to this variability are PD-L1 expression levels and immune cells...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Imaging Biol
Auteurs principaux: Li, Wenping, Wang, Yuchuan, Rubins, Daniel, Bennacef, Idriss, Holahan, Marie, Haley, Hyking, Purcell, Mona, Gantert, Liza, Hseih, SuChun, Judo, Michael, Seghezzi, Wolfgang, Zhang, Shuli, van der Veen, Elly L., Lub-de Hooge, Marjolijn N., de Vries, Elisabeth G.E., Evelhoch, Jeffrey L., Klimas, Michael, Hostetler, Eric D.
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910264/
https://ncbi.nlm.nih.gov/pubmed/33104972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01558-w
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