The Volatile Oil of Zanthoxylum bungeanum Pericarp Improved the Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota to Attenuate Chronic Unpredictable Stress-Induced Anxiety Behavior in Rats

BACKGROUND: Anxiety disorders (ADs) are the most prevalent mental disorders worldwide. Stress-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis and dysbiosis of gut microbiota seem to contribute to the onset of ADs. This study was designed to investigate the ameliorative effect of...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Wei, Daneng, Zhao, Yafei, Zhang, Mengmeng, Zhu, Lei, Wang, Li, Yuan, Xing, Wu, Chunjie
Format: Artigo
Idioma:Inglês
Publicat: Dove 2021
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910097/
https://ncbi.nlm.nih.gov/pubmed/33654382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S281575
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