Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics

Communications between actin filaments and integrin-mediated focal adhesion (FA) are crucial for cell adhesion and migration. As a core platform to organize FA proteins, the tripartite ILK/PINCH/Parvin (IPP) complex interacts with actin filaments to regulate the cytoskeleton-FA crosstalk. Rsu1, a Ra...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Yang, Haibin, Lin, Leishu, Sun, Kang, Zhang, Ting, Chen, Wan, Li, Lianghui, Xie, Yuchen, Wu, Chuanyue, Wei, Zhiyi, Yu, Cong
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2021
Teme:
Biochemistry and Chemical Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909951/
https://ncbi.nlm.nih.gov/pubmed/33587032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64395
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